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Emerging perspectives on precision therapy for Parkinsons disease: multidimensional evidence leading to a new breakthrough in personalized medicine

In summary, ferroptosis is intricately linked to liver inflammation, and targeting ferroptosis pathways holds promise for reducing inflammation and slowing NAFLD progression

Abbreviations CVD: Cardiovascular disease CHD: Congenital heart disease AAA: Abdominal aortic aneurysm TAD: Thoracic aortic dissection CAD: Coronary artery disease Hcy: Homocysteine HHcy: Hyperhomocysteinemia CBS: Cystathionine -synthase MTHFR: 5,10-Methylenetetrahydrofolate reductase ECs: Endothelial cells VSMCs: Vascular smooth muscle cells HUVECs: Human umbilical vein endothelial cells HASMCs: Human aortic smooth muscle cells ECM: Extracellular matrix MMPs: Matrix metalloproteinases PDGF: Platelet-derived growth factors References Zaric BL, Obradovic M, Bajic V, Haidara MA, Jovanovic M, Isenovic ER (2019) Homocysteine and hyperhomocysteinaemia

Interestingly, the highest concentrations of TMAO in dietary meats are found in fish and marine invertebrates [54]

[DOI] [PubMed] [Google Scholar] 245.Hartmann G, Vassileva V, Piquette-Miller M
