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In one study, targeted metabolomic analysis of the CSF of 14 MDD patients who were not taking medication, 14 MDD patients in remission, and 18 healthy controls was performed

The cyclic reactions are shown in Figure 3

The GH secretagogues ipamorelin and GH-releasing peptide-6 increase bone mineral content in adult female rats (2000) Svensson J, Lall S, Dickson SL, Bengtsson BA, Rmer J, Ahnfelt-Rnne I, Ohlsson C, Jansson JO Journal of Endocrinology 165(3):569577 Participants Adult female Sprague-Dawley rats Methodology SC treatment with ipamorelin or GHRP-6

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doi: 10.1016/j.neuroscience.2014.11.025CrossRefGoogle ScholarPubMed Xie, X., Shen, Q., Yu, C., Xiao, Q., Zhou, J., Xiong, Z., Fu, Z