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A study by Shahram Akbaraly titled Schizophrenia and the Risk of Dementia, published in The Lancet Psychiatry (2018), found that people with schizophrenia are nearly twice as likely to develop dementia compared to the general population

5-Amino-1-MQ mechanism of action 5-Amino-1MQ acts as a selective small molecule inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme that methylates nicotinamide using S-adenosylmethionine (SAM) as a methyl donor

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