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Combination use is not studied, but additive caloric restriction effects could amplify hypoglycemia risk in patients who are also reducing dietary intake
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Dual-target inhibitors of bromodomain and extra-terminal proteins in cancer: A review from medicinal chemistry perspectives
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The mesenchymal phenotype has also been connected with SMAD3 activity in BRAFi persisters, and SMAD3 signaling led to the acquisition of drug resistance via activation of known drug-resistance genes, such as EGFR and AXL 41
