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[DOI] [PubMed] [Google Scholar] Tirosh I, Izar B, Prakadan SM, Wadsworth MH, Treacy D, Trombetta JJ, Rotem A, Rodman C, Lian C, Murphy G, et al

This trend may indicate increased inbreeding in the low-endemic settings, but larger sample sizes are needed to confirm this
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doi: 10.1038/s41418-022-01003-1 205 ZoghbiHYBeaudet al

This was accompanied by a reduction of NADPH production in the PPP, which further decreased the low intrinsic antioxidant reserve of neurons, making them more susceptible to ischemic stress
