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26 Sirtuins manipulate the metabolism reprogramming via directedly altering the activity of metabolic enzymes by NAD + -dependent modification or changing their expression by regulating transcription factors

donovani , and in the latter even over the pH range 4.87.8 (Ortz et al

H., Miller, K

After entry into nucleus, Hsp90 dissociates from the Hsp90/PB1/PB2 complex and forms a new functional complex with polymerase acidic protein (PA)
