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NR-SAFE: a randomized, double-blind safety trial of high dose nicotinamide riboside in Parkinsons disease

Individuals adhering to a vegetarian or vegan diet, those aged 50 and above, or people experiencing malabsorption issues are at a higher risk of developing a deficiency

Some users find optimal results at 20 units and stay there

Natural forms like methylcobalamin, adenosylcobalamin, and hydroxocobalamin are generally more bioavailable and better tolerated than synthetic forms like cyanocobalamin, especially in people with increased risk of deficiency

Linebarger: And we charge about 250 $250 for a bottle, and that bottle will last 30 to 60 days