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Vitamin B12 is reduced to cobalamin regardless of form (cyan-, methyl-, adenosyl-, hydroxo-) then re-assembled as methylcoblamin by MS for use in the cytosol, or adenosylcobalamin by MM for use in the mitochondria

Above that, molecules have a genuinely harder time crossing the gut lining into circulation

It is generally considered to have a longer-lasting effect than cyanocobalamin

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