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The calcium overload stimulates the production of reactive oxygen species (ROS) through NADPH oxidase (NOX2), which inhibits glucose transporters and reduces substrate transfer, resulting in impaired respiration [62]

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[DOI] [PubMed] [Google Scholar] 33.Kiremidjian-Schumacher L, Roy M, Wishe HI, Cohen MW, Stotzky G

Research indicates that the decline in estrogen, testosterone, growth hormone (GH), and thyroid hormone (TH) levels is closely associated with cardiovascular dysfunction, increased vascular stiffness, elevated inflammation, and myocardial remodeling