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(iii) thus, the rate of glycolysis (that would determine the rate of glucose consumption) could only be dictated by integration of allosteric signals on the only remaining regulated enzyme, the phosphofructokinase-1
Several drugs can produce addictive behavior in humans and animals, including psychostimulants, opioids, cannabinoids, nicotine, and alcohol
19 In addition, because the signaling pathways downstream from IR and IGF-IR share many components, the characterization of these signaling events may not distinguish which receptor is initiating the signal
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