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A heterozygous effect for PINK1 mutations in Parkinsons disease

Loss of neuronal GSH has also been linked to microglial activation and complement-mediated neurodegeneration, further emphasizing the link between redox imbalance and immune dysregulation (Hashimoto et al., 2023)

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MouzakiMComelliEMArendtBMBonengelJFungSKFischerSEet alIntestinal microbiota in patients with nonalcoholic fatty liver disease

This results in immune cells congregating in the thyroid gland, and eventually losing their ability to differentiate the thyroid gland from a foreign invader (like a virus or bacteria)