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The copper ion appears to stabilize and deliver GHK to cells

Vitamin B12 modulates the transcriptome of the skin microbiota in acne pathogenesis

doi: 10.1080/00218839.2020.1844462 44

The breakdown side of the equation involves enzymes called matrix metalloproteinases (MMPs) , particularly MMP-1

Folate deficiency can coexist with B12 deficiency and may mask or modify the haematological picture, so checking serum folate levels is also important
