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Treatment and Management Strategies Management of carnitine biosynthesis disorders often involves carnitine supplementation to restore normal metabolic function

25 In two randomized placebo-controlled trials, totaling 1257 patients with diabetic neuropathy, Sima and colleagues failed to find any significant electrophysiological change in patients treated with 500 or 1,000 mg ALC, although a significant improvement in the vibration perception threshold was reported

Interest in the proposed therapeutic benefits of nutritional ketosis has been growing the past recent years

A.et al (2019)

Therefore, ERGO may suppress the kynurenine pathway possibly via suppressing the CXCL9-induced activation of IDO