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If purification is performed at pH6.8, the purified product must be treated with acid immediately to prevent oxidation

10.1016/j.abb.2016.10.016 46 MarmisolleI.ChacnE.MansillaS.RuizS.BresqueM.MartnezJ.et al (2025)

a single mutant copy of the SOD1 gene is sufficient to cause the disease

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While studies like those of Kennedy et al
