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These are outcomes that change health trajectories, reduce comorbidity risks, and fundamentally alter quality of life
Lost productivity, inability to participate in recreational activities, and the frustration of multiple failed treatments contribute to decreased quality of life
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Age-related factors Older people are at more risk because with age the production of stomach acid and intrinsic factor (a protein necessary for B12 absorption) can decrease
The gut as a source of inflammation in chronic kidney disease
