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Description
Mechanisms of nanoparticle-induced oxidative stress and toxicity
Studies in the model organism Caenorhabditis elegans have demonstrated that different FOXO isoformsparticularly DAF-16Aexert a significant influence on lifespan extension by activating or repressing specific genes such as gst-20 and srr-4, which either promote or inhibit longevity-associated mechanisms
J Exp Med
doi: 10.1136/bmj.n1804 [DOI] [PMC free article] [PubMed] [Google Scholar] 170
Cell signalling
