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Description
Prodrug approaches to enhancing the oral delivery of poorly permeable drugs
313 High expression of claudin-2, a tight junction protein, can increase the permeability of the intestinal barrier and disrupt its structure
Research Use Only
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Targeting p53 for the treatment of lung cancer Many anti-cancer therapeutics kill cancer cells by inducing DNA damage which triggers WT p53-mediated apoptosis and/or cell cycle arrest/cell senescence
