glutathione reductase enzyme function Glutathione-Related System: (GR), Glutathione Transferases (GSTs) and Glutathione Peroxidases (GPXs) Glutathione Homeostasis and Functions: Potential

Description

Today lesson make me realize, as an aspiring pharmacist we should understand the "why" behind each treatment

10.1016/j.neuro.2012.08.011 206 Rahil-KhazenR.BolannB

This is in consistent with another study showing that pre-treatment with triptolide, a diterpenoid epoxide protected Wistar rat from myocardial ischemia/reperfusion injuries by suppressing the production of pro-inflammatory cytokines (TNF-, IL-1, and IL-6) and inducing Nrf2-regulated antioxidant enzymes (SOD, GSH, GPx, and HO-1) (Yu et al., 2016)

The combination is proposed of reduced glutathione and Highly Active Anti-Retroviral Therapy having at least one pharmaceutical composition selected from the group of Nucleoside/tide Reverse Transcriptase Inhibitors (NRTIs), Protease Inhibitors (PIs), and Non-nucleoside Reverse Transcriptase Inhibitors (NnRTIs)