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Finally, high levels of follicle-stimulating hormone (FSH) in response to estrogen deficiency might also contribute to the high BMAT and low bone mass phenotype in OVX mice as treatment with a polyclonal antibody to FSH significantly reduces BMAT volume and increases bone mass in mice (308)

As acetyl-CoA stores are depleted, the synthesis of NAGA an important cofactor of CPS I from acetyl-CoA and glutamate by NAGA synthetase is decreased

A., Hosseini, S

OToole James
Sending these labs prior to metabolic manipulations (e.g., IV arginine) may help provide a clear diagnosis later
