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Nerve and Brain Health: Prevents neuropathy, supports neurotransmitter synthesis, improves mood and memory
GHK-Cu for collagen synthesis and tissue remodelling
However, its C-terminal end can be cleaved by carboxypeptidase A, and removal of the last leucine residue (L585) weakens receptor binding, reducing its half-life from 20 days to 3.5 days in humans
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This review describes the structural diversity of these pro-moieties, relevant cleavage mechanisms and recent advances in the design of phosphonate prodrugs
Watts, D
