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-Tocopherol is a powerful antioxidant, but in high concentrations, it can become a pro-oxidant

If Phase 1 runs faster than Phase 2/3, reactive intermediates build up and recirculate (enterohepatic recycling), causing headaches, fatigue, nausea, skin flares, or brain fog

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Upping antioxidants like glutathione would likely benefit premature graying by combating the oxidative damage that is happening to the pigment producing cells called melanocytes, she said