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It helps doctors pinpoint if gastrointestinal issues have systemic repercussions

To better understand the resistance to HFD-induced weight gain in DKO mice, we placed male and female DKO and littermate control mice on HFD for 4 weeks before differences in body weight were apparent

doi: 10.1038/jcbfm.2014.8

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However, once LCR was tested alone using the same dosage, but for a longer period (i.e., 24 wk), no significant effect was found
