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Direct comparison data dont exist, but we can extrapolate from individual trials

doi: 10.1093/nar/gky427 [DOI] [PMC free article] [PubMed] [Google Scholar] 36.Giulianelli S, Molinolo A, Lanari C

Professor Ngs research contributions to AOD-9604 development include: Synthesis and characterization of the modified C-terminal growth hormone fragment with enhanced stability Design of the tyrosine N-terminal modification to improve peptide stability and half-life Preclinical studies demonstrating lipolytic effects in obese animal models Advancement of the peptide through multiple phases of clinical development Investigation of mechanisms underlying beta-3-adrenergic receptor modulation His work established the foundation for understanding peptide-based approaches to metabolic regulation, though clinical translation ultimately proved unsuccessful