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This review focuses on the analysis of literature data about the influence of certain probiotic strains on the pathogenesis and course of SLE as immunomodulators and a new therapy strategy that seeks to achieve a synergistic effect with the help of an additional probiotic in combination with dietary supplements gingerols or vitamin D

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and patients with glutathione-S-transferase M1 (proinflammatory-cytokine producer macrophages) null and M1 and T1 (Type 1 helper CD4 + lymphocytes) double null polymorphisms had increased mortality suggesting that antioxidant therapy becomes fundamental for those patients (109)