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There are two known acetyl-CoA synthetase isoforms present in yeast cells - Acs1 and Acs2 (encoded respectively by ACS1 and ACS2 ) 26,46

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We acknowledge the assistance of the University of Texas Southwestern Tissue Management Shared Resource, a shared resource at the Simmons Comprehensive Cancer Center, which is supported in part by the National Cancer Institute under award number P30CA142543

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Administration of cruciferous-derived compounds, such as sulforaphane, may increase Glutathione and Glutathione-related enzymes

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10.1007/s00253-018-9155-6 75

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We also consider how the cell heterogeneity inherent in cancerous tumors is involved in the development of drug resistance

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