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Specifically, Que, BBR, and curcumin can exert anti-apoptotic neuroprotective effects in the OGD model by inhibiting the activation of the PI3K/Akt pathway, while ginkgolides and Que can also counteract apoptosis in hypoxic-ischemic brain injury by activating the target AMPK

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When ERK1/2 signaling was inhibited, the beneficial effects of BPC-157 on wound closure were significantly reduced, confirming this pathways importance in the peptides mechanism of action

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Medical use: Despite early research into sleep and hormone regulation, DSIP has not been adopted into mainstream clinical practice

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Krivic, A

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We also searched clinical guidelines and our personal archives of references, and screened the reference lists of studies retrieved by the searches

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