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This article begins with an overview of basic pathological mechanisms and offers a comprehensive overview of relevant therapeutic approaches and future development directions, aiming to facilitate the transition of the field from traditional generalized therapies to personalized precision medicine and to bridge the long-standing gap between basic research and clinical practice.

Through integrated analysis of single-cell RNA sequencing data, clinical specimens, and in vivo and in vitro experiments, we identified FAP+ CAFs as the predominant stromal population associated with poor clinical outcomes and immunosuppressive features

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This Review from Shokrollah Elahi considers how erythroid cells including erythroid progenitors and precursors and mature red blood cells can modulate immunity in different settings, including in infection, autoimmunity and cancer.

This amino acid has numerous health benefits due to its involvement in the respiratory chain