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Conserved class B GPCR activation by a biased intracellular agonist
Its ability to bring uniformity to complexions is appealing to those with an uneven skin tone (hyperpigmentation) from acne, scarring or lifestyle factors (for example: sun damage, age, hormones)
MBio 7 , e0044316 (2016)
54 Infants with MD present with high levels of dihydroxyphenylalanine, the precursor of catecholamines, suggesting reduced DH activity
