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The development of PCSK9 monoclonal antibodies including evolocumab and alirocumab have been demonstrated to lower LDL-C levels as well as CVD risks (Hadjiphilippou and Ray, 2017

Research has shown that it can be over to 10 million times more potent than brain- deduced neurotrophic factor( BDNF) in promoting neuronal growth and connectivity

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doi: 10.1016/j.molimm.2007.06.149
