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The breadth of documented activity reflects what the original investigators have described as systems-level pharmacology: rather than acting through a single high-affinity receptor, BPC-157 appears to modulate multiple intersecting cellular pathways including nitric oxide signalling, growth-factor receptor expression, dopamine and serotonin metabolism, and angiogenic vessel formation

Retrieved 19 March 2026

Increased MMA levels cause demyelinating defects in the nervous system and elevate propionic acid, resulting in metabolic acidosis
