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We also transfected primary corneal endothelial cells with ATF4 siRNA to knock down ATF4 and assessed MMP
It is well-established that VIP, an immunoinhibitory neuropeptide secreted from perifollicular sensory nerve endings, prevents the HFs from IP collapse 93 and promotes melanogenesis in the B16F10 cell line and normal human melanocytes basically by activating the PKA/CREB/MITF signaling pathway 94
10.1038/s41591-018-0165-9
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