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En estudios a largo plazo utilizando moscas de la fruta (Drosophila melanogaster) y modelos de roedores, la administracin de Epithalon se asocio con aumentos estadisticamente significativos en la esperanza de vida media y maxima

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A mild beneficial effect in patients with AD was reported after 12 weeks of treatment with 100 mg/day of a thiamin derivative (thiamin tetrahydrofurfuryl disulfide), but this study was not placebo-controlled (70)

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