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Description
Elevated serum zonulin levels, as well as bacterial dysbiosis and a leaky gut barrier, have been observed in patients with rheumatoid arthritis, while subclinical intestinal inflammation has been observed in patients with ankylosing spondylitis [74, 75]
Caspase-1 inhibition prevents glial inflammasome activation and pyroptosis in models of multiple sclerosis
It has a protective effect on cardiovascular diseases (138) and can protect nerves through the BBB (139) (see Table 6 )
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The peptide's ability to promote tendon fibroblast migration, enhance collagen synthesis, and support vascular ingrowth addresses key biological requirements for tendon repair
