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Clinical protocols in integrative oncology studies commonly involve a detailed baseline assessment of tumour sub-type, receptor status, comorbidities, organ function, and concurrent medications including an organized evaluation of pre-existing and current use of supplements to adjust for possible confounding factors (230)

They emphasize that cholinesterase inhibitors may not help all cognitive symptoms and could disrupt natural ACh balance, showing that AChs effects on memory are complex and require further investigation

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LC-quadrupole/Orbitrap high-resolution mass spectrometry enables stable isotope-resolved simultaneous quantification and 13 C-isotopic labeling of acyl-coenzyme A thioesters