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Elevated Ca 2 concentrations within the mitochondria can trigger an increase in H 2 O 2 production, ultimately leading to mitochondrial dysfunction, excessive ROS generation, and initiation of apoptosis [448,454]

T.CasserlyB.HarringtonE

Antioxidant activities and phenolic compounds of pigmented rice bran extracts

Steady glutathione levels sustain the brightening effect, which is why skipping treatments tends to slow visible progress

Nicergoline has been shown to be an effective drug for preventing neuronal vulnerability due to experimentally induced nerve growth factor deprivation and improved the function of cholinergic and catecholaminergic neurotransmitters in rats in vivo [64]