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Accordingly, the canonical polybasic furin cleavage site has been reported in several enveloped viruses, including Herpes-, Corona-, Flavi-, Toga-, Borna-, Bunya-, Filo-, Orthomyxo-, Paramyxo-, Pneumo , and Retroviridae 332

Br J Cancer 1995;72:1173-9 63 -Arenas J ea

NTD The NTD accounts for more than half of the size of the AR (residues 1555), and its entirety is encoded by exon 1

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Importantly, in these experimental models, pre-hypoxic treatment with sodium 2-[5-(4-chlorophenyl)-pentyl]-oxirane-2-carboxylate (POCA) or oxfenicine, both inhibitors of CPT I, prevents membrane and cytosolic LCAC accumulation in early ischaemia and the genesis of electrophysiological derangements (Yamada et al., 1994)