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The paper by Simes et al

Angelidou A, Alysandratos K-D, Asadi S, Zhang B, Francis K, Vasiadi M et al (2011) Brief report: allergic symptoms in children with autism spectrum disorders

[138] to get an extensive comprehension of the metabolic changes coming about because of AFB1 openness

Since these enzymes require lipid hydroperoxide for their activation, the overexpression of GPX4 results in a reduction in the cellular lipid hydroperoxide level, which effectively inactivates PTGS and LOX, eventually inhibiting eicosanoid synthesis (3739)

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