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For chronic obstructive pulmonary disease targeting immunoproteasomes such as with ONX-0914 nanoparticles simultaneously suppresses both M1 and M2 polarization alleviating emphysema (75)

[DOI] [PMC free article] [PubMed] [Google Scholar] 92.Rajagopal S, Bassoni DL, Campbell JJ, Gerard NP, Gerard C, Wehrman TS

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However, since the protein is interacting with the trehalose, presumably through hydrogen bonds, the relaxation time deviates from linearity

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