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Siddiqua TJ, Ahmad SM, Ahsan KB, et al
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2.13 Mass spectrometry 2.13.1 Hydrogen-deuterium exchange mass spectrometry (HDX-MS) Time-resolved spontaneous hydrogen-deuterium exchange (HDX) of covalently bonded hydrogens of a protein with deuterium in solution provides information about protein conformation, flexibility, and solvent accessibility (Englander et al., 2016)
