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Following DNA isolation, unmethylated cytosine nucleotides were converted into uracil with the EZ DNA Methylation-Gold Kit (Zymo Research, Irvine, California)
This method ensures maximum absorption and rapid correction of deficiency levels
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Patients with Leber's Disease: Vitamin B12 levels may exacerbate optic nerve atrophy
Note that 9 mg and 12 mg are now the Phase-3-validated doses, while 1 mg, 4 mg, and 8 mg remain Phase 2 / research reference points
