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Tirzepatide is a dual GLP-1/GIP receptor agonist

It actively helps rebuild skin elasticity, refine texture, and brighten uneven tone, so your skin looks lifted, clearer, and more youthful with consistent use

doi:10.1016/j.jmb.2008.01.051

119 The most prominent action of many peptides (i.e., bombesin, thyrotropin-releasing hormone, CRF, neurotensin) on gastric lesions 120 - 128 which appears when applied within the specific hypothalamic and brain stem sites or into the cerebrospinal fluid, 128 requires a corresponding effect from periphery