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FIGURE 3 In cancer, hypermethylation of CpG islands in the promoter sequence of some genes results in gene silencing by suppressing the transcriptional activity of tumor suppressor genes (Dehan et al., 2009)
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Activation of GLP-1 receptors on vascular smooth muscle cells reduces the autoregulatory response in afferent arterioles and increases renal blood flow

Front Pharmacol (2022) 13:995061
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