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[DOI] [PubMed] [Google Scholar] 262.Taguchi N, Homma T, Aoki H, Kunisada T

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Liu et al., 2012)

CB-839 (Telaglenastat), a potent, reversible, and selective small-molecule inhibitor that targets GLS-1 and has a half-maximal inhibitory concentration (IC 50 ) of 24 nM for recombinant human glutaminase C, has been investigated in solid tumors and in AML, diffuse large B-cell lymphoma, and multiple myeloma cells alone or in combination with other anticancer drugs (10, 11, 2026)