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OS arises from a disruption in redox homeostasis, where an overproduction of reactive oxygen species (ROS) overwhelms endogenous antioxidant defenses, leading to oxidative damage to lipids, proteins, and DNA (Sies et al., 2024)
It will be important to further determine whether these copper transporters at the plasma membrane play tumor type-specific roles in mediating copper uptake
doi: 10.1007/s40265-018-1045-9 36 TaylorPNAlbrechtDScholzAGutierrez-BueyGLazarusJHDayanCMet al
