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and finally employs an endosomal enzyme, cathepsin L (CTSL) for fusogenic release of its viral genome
In two recent studies, researchers used large-scale CRISPR-based screening to test nearly all possible single base changes in the BRCA2 gene, which is often linked to inherited risk in breast and ovarian cancers
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Additionally, IGF-1 can mediate anti-inflammatory effects through the PI3K pathway (80,81)
