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Moreover, iPSC-derived astrocytes have also shown promise in modelling AD-related cellular changes, such as early atrophy and followed by hypertrophykey events in disease progression

596 Fat mass and obesity (FTO) protein and fat mass are closely related to obesity and lipid metabolism

Furthermore, oxLDL induces the release of pro-inflammatory cytokines, perpetuating inflammation and promoting the progression of atherosclerotic plaques [73]

IL-17, which has a variable inflammatory effect that promotes the migration of inflammatory cells to inflammatory tissues, levels of IL-17 were found to decrease in lung homogenates of fibrotic mice treated with vitamin C (126)

Although trace metals such as iron and copper are essential for numerous physiological processes, their accumulation or dysregulation can lead to the generation of ROS, contributing to oxidative damage, lipid peroxidation, and impairment of both enzymatic and non-enzymatic antioxidant defenses [69]