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Silibinin strongly inhibits growth and survival of human endothelial cells via cell cycle arrest and downregulation of survivin, Akt and NF-kappaB: implications for angioprevention and antiangiogenic therapy

Pharmacological inhibition of mitochondrial -oxidation (e.g., with 4-bromocrotonic acid) or peroxisomal -oxidation (e.g., with thioridazine) under glucose-deprived conditions markedly compromises oligodendrocytes survival and optic nerve conduction, underscoring the central role of this catabolic pathway in white matter energy homeostasis

To investigate this possibility, we used high-resolution respirometry and analysed various respiratory states in the striatal tissues of mutants and controls at 3 months and 8 months

This initial course replenishes body stores

doi: 10.3892/ol.2021.13042 242 XiaoHXuXDuLLiXZhaoHWangZet al