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Role of Salicylic Acid in Plants

Notably, studies have demonstrated that peroxisome proliferator-activated receptor coactivator 1 (PGC1) (36), which is highly expressed in drug-resistant ovarian cancer cells, promotes the transcription of heat shock protein (HSP70)

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When microglia surface receptors (such as TLR2 or TLR4) interact with soluble -Syn, it could potentially result in elevated oxidative stress levels and trigger the activation of inflammatory pathways that involve NF-B and mitogen-activated protein kinase (Soraci et al., 2023), thus facilitating PD advancement