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(A-D) Values are the mean of three independent technical replicates and at least two biological replicates

Our observation that the recovery of hepatic GSH levels after EtOH administration in young mice is less than complete is consistent with a pervious finding in mice [22] but contrasts with other studies in young rats, in which hepatic GSH levels were fully recovered by 18 hr [14]

The transcellular route uses the movement of molecules through the cells, passing through apical and basolateral membranes [286]

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The present study, for the first time, demonstrates an underlying mechanism for the activation of eNOS by BPC 157 on stimulating the Cav-1 phosphorylation and reducing the binding of eNOS to Cav-1