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Description
The interest traces to a 2014 Nature paper showing that knocking down NNMT in fat and liver protected mice against diet-induced obesity, glucose intolerance, and fatty liver, partly by shifting adipose NAD+ and SAM levels [4]

But I have come across similar reports describing something similar to a 48 hour half-life
[DOI] [PubMed] [Google Scholar] 12.Dallongeville J, Fruchart JC, Auwerx J

Heres what you can expect

A: AOD-9604 stands for Anti-Obesity Drug 9604
